Article
The role of pygopus in the differentiation of intracardiac valves in Drosophila.
Genesis (New York, N.Y. : 2000) - 1 Jan 2014
Tang Min, Yuan Wuzhou, Bodmer Rolf, Wu Xiushan, Ocorr Karen
Abstract excerpt
Cardiac valves serve an important function; they support unidirectional blood flow and prevent blood regurgitation. Wnt signaling plays an important role in the formation of mouse cardiac valves and cardiac valve proliferation in Zebrafish, but identification of the specific signaling components involved has not been addressed systematically. Of the components involved in Wnt signal transduction, pygopus (pygo),...
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