Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Improvement of reading frame maintenance is a common function for several tRNA modifications.

The EMBO journal - 3 Sept 2001

Urbonavicius J, Qian Q, Durand J M, Hagervall T G, Björk G R

Abstract excerpt

Transfer RNAs from all organisms contain many modified nucleosides. Their vastly different chemical structures, their presence in different tRNAs, their occurrence in different locations in tRNA and their influence on different reactions in which tRNA participates suggest that each modified nucleoside may have its own specific function. However, since the frequency of frameshifting in several different mutants...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta-Galactosidase
Share to Oligodeoxyribonucleotides
Share to Reading Frames

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to RNA, Transfer

Share to RNA, Transfer, Amino Acid-Specific

Share to RNA, Transfer, Amino Acyl

Share to RNA, Transfer, Leu

Share to RNA, Transfer, Phe

Source

Open in PubMed Open full text

Identifiers

PMID: 11532950
DOI: 10.1093/emboj/20.17.4863
PMCID: PMC125605

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Improvement of reading frame maintenance is a common function for several tRNA modifications.PMID 11532950Read ↗

Biosynthesis and function of posttranscriptional modifications of transfer RNAs.Semantic proximity Read ↗

Methylated nucleosides in tRNA and tRNA methyltransferasesSemantic proximity Read ↗

Transfer RNA modifications that alter +1 frameshifting in general fail to affect -1 frameshifting.Semantic proximity Read ↗

Role of tRNA modification in translational fidelity.Semantic proximity Read ↗

Lost in Translation: Defects in Transfer RNA Modifications and Neurological DisordersSemantic proximity Read ↗

Modification of the wobble uridine in bacterial and mitochondrial tRNAs reading NNA/NNG triplets of 2-codon boxesSemantic proximity Read ↗

The phenotype of many independently isolated +1 frameshift suppressor mutants supports a pivotal role of the P-site in reading frame maintenance.Semantic proximity Read ↗

Hypomodified tRNA in evolutionarily distant yeasts can trigger rapid tRNA decay to activate the general amino acid control response, but with different consequencesSemantic proximity Read ↗

Tertiary structure base pairs between D- and TpsiC-loops of Escherichia coli tRNA(Leu) play important roles in both aminoacylation and editing.Semantic proximity Read ↗

[Wobble modification defect suppresses translational activity of tRNAs with MERRF and MELAS mutations].Semantic proximity Read ↗

Queuosine modification of tRNA: its divergent role in cellular machinerySemantic proximity Read ↗

Transfer RNA modification and infection – Implications for pathogenicity and host responsesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.