Article
Folded HasA inhibits its own secretion through its ABC exporter.
The EMBO journal - 3 Sept 2001
Debarbieux L, Wandersman C
Abstract excerpt
Gram-negative bacterial proteins secreted by ABC exporters carry a secretion signal in their carboxylic extremities. This characteristic suggests that the polypeptide needs to be fully synthesized before it can be secreted and, therefore, presumably may fold at least in part before its secretion. We investigated the relationship between folding and secretion using HasA, a hemoprotein of Serratia marcescens...
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