Article
Regulation of Laloo by the Xenopus C-terminal Src kinase (Xcsk) during early vertebrate development.
Oncogene - 23 Aug 2001
Song Y, Cohler A N, Weinstein D C
Abstract excerpt
Mesoderm formation in the frog, Xenopus laevis, is dependent on the activity of one or more members of the Src family kinases; the molecular interactions underlying this requirement are not well understood. The C-terminal Src Kinase (Csk) is a potent inhibitor of Src activity, and is required for normal mammalian development; here we report the characterization of Xenopus Csk (Xcsk). Xcsk is widely expressed...
Topics
- Amino Acid Sequence
- Animals
- CSK Tyrosine-Protein Kinase
- Gene Expression Regulation, Developmental
- In Situ Hybridization
- Mesoderm
- Molecular Sequence Data
- Mutagenesis
- Mutation
- Protein Binding
- Protein Structure, Tertiary
- Protein-Tyrosine Kinases
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-fyn
- Reverse Transcriptase Polymerase Chain Reaction
- Sequence Homology, Amino Acid
- Time Factors
- Xenopus