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Article

Very large long-term effective population size in the virulent human malaria parasite Plasmodium falciparum.

Proceedings. Biological sciences - 7 Sept 2001

Hughes A L, Verra F

Abstract excerpt

It has been proposed that the virulent human malaria parasite Plasmodium falciparum underwent a recent severe population bottleneck. In order to test this hypothesis, we estimated the effective population size of this species from the patterns of nucleotide substitution at 23 nuclear protein-coding loci, using a variety of methods based on coalescent theory. Both simple methods and phylogenetically based...

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Identifiers

PMID: 11522206
DOI: 10.1098/rspb.2001.1759
PMCID: PMC1088819

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