Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

1,25-dihydroxyvitamin D3 and retonic acid analogues induce differentiation in breast cancer cells with function- and cell-specific additive effects.

Breast cancer research and treatment - 1 May 2001

Wang Q, Lee D, Sysounthone V, Chandraratna RAS, Christakos S, Korah R, Wieder R

Abstract excerpt

Vitamin D3 derivatives and retinoids can induce cell cycle arrest, differentiation and cell death in many cell lines. These compounds can act cooperatively in some of their functions and may be of potential use either individually or in combination in the treatment of breast cancer. The effects of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3), all-trans retinoic acid (ATRA) and several analogues were evaluated on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Calcitriol

Share to Cell Cycle

Share to Cell Differentiation

Share to Gene Expression Regulation, Neoplastic

Share to Tretinoin

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 11519864
DOI: 10.1023/a:1010643323268

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

1,25-dihydroxyvitamin D3 and retonic acid analogues induce differentiation in breast cancer cells with function- and cell-specific additive effects.PMID 11519864Read ↗

Differential effects of 1,25-dihydroxyvitamin D3 and tetradecanoylphorbol acetate on cell cycle and apoptosis of MCF-7 cells and a vitamin D3-resistant variant.Semantic proximity Read ↗

Vitamin D and cancer: an update of in vitro and in vivo dataSemantic proximity Read ↗

Targets of Vitamin D Receptor Signaling in the Mammary GlandSemantic proximity Read ↗

CYP11A1‑derived vitamin D hydroxyderivatives as candidates for therapy of basal and squamous cell carcinomasSemantic proximity Read ↗

Vitamin D regulates the phenotype of human breast cancer cells.Semantic proximity Read ↗

A synergistic antiproliferation effect of curcumin and docosahexaenoic acid in SK-BR-3 breast cancer cells: unique signaling not explained by the effects of either compound aloneSemantic proximity Read ↗

Vitamin D Effects on Cell Differentiation and Stemness in CancerSemantic proximity Read ↗

Retinoids, Carotenoids, and Human Breast Cancer Cell Cultures: A Review of Differential EffectsSemantic proximity Read ↗

Specific chemopreventive agents trigger proteasomal degradation of G1 cyclins: implications for combination therapy.Semantic proximity Read ↗

Retinoic acid and ascorbic acid act synergistically in inhibiting human breast cancer cell proliferationSemantic proximity Read ↗

Vitamin D and differentiation in cancerSemantic proximity Read ↗

Modulation of cell cycle control by vitamin D3 and its analogue, EB1089, in human breast cancer cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.