Article
Insulin-like growth factor-I gene expression patterns during spontaneous repair of acute articular cartilage injury.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Jul 2001
Fortier L A, Balkman C E, Sandell L J, Ratcliffe A, Nixon A J
Abstract excerpt
This study evaluated the constitutive insulin-like growth factor-I (IGF-I) gene expression pattern in spontaneously healing cartilage defects over the course of 16 weeks, and correlated the tissue morphology and matrix gene expression with IGF-I mRNA levels. Full-thickness 15 mm cartilage defects were debrided in the femoral trochlea of both femoropatellar joints of 8 horses and the healing defects examined 2, 4,...
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