Article
Patterns of Gene Expression in a Rabbit Partial Anterior Cruciate Ligament Transection Model
4 Dec 2009
Abstract excerpt
BACKGROUND: The inconsistency in healing after anterior cruciate ligament (ACL) repair has been attributed to ACL fibroblast cellular metabolism, lack of a sufficient vascular supply, and the inability to form a scar or scaffold after ligament rupture because of the uniqueness of the intra-articular environment. Hypotheses (1) Stress deprivation in the surgically transected ACL will increase matrix...