T lymphocytes infiltrating advanced grades of cervical neoplasia. CD8-positive cells are recruited to invasion.

doi:10.1002/1097-0142(19951015)76:8<1411::aid-cncr2820760817>3.0.co;2-v

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T lymphocytes infiltrating advanced grades of cervical neoplasia. CD8-positive cells are recruited to invasion.

Cancer - 15 Oct 1995

Edwards R P, Kuykendall K, Crowley-Nowick P, Partridge E E, Shingleton H M, Mestecky J

Abstract excerpt

BACKGROUND: Impaired cellular immunity appears to be a risk factor for progression of cervical neoplasia, but the immunobiology of neoplastic progression is poorly understood. The objective of this study was to characterize the subpopulations of T lymphocytes that infiltrate various grades of cervical neoplasia including metaplasia to invasive cancer in immunocompetent women. METHOD: In 65 patients with a...

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T lymphocytes infiltrating advanced grades of cervical neoplasia. CD8-positive cells are recruited to invasion.

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