Article
Purification of a pluripotent neural stem cell from the adult mouse brain.
Nature - 16 Aug 2001
Rietze R L, Valcanis H, Brooker G F, Thomas T, Voss A K, Bartlett P F
Abstract excerpt
The adult mammalian central nervous system (CNS) contains a population of neural stem cells (NSCs) with properties said to include the generation of non-neural progeny. However, the precise identity, location and potential of the NSC in situ remain unclear. We purified NSCs from the adult mouse brain by flow cytometry, and directly examined the cells' properties. Here we show that one type of NSC, which expresses...
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