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Article

Sialylation of human IgG-Fc carbohydrate by transfected rat alpha2,6-sialyltransferase.

Biochemical and biophysical research communications - 17 Aug 2001

Jassal R, Jenkins N, Charlwood J, Camilleri P, Jefferis R, Lund J

Abstract excerpt

A recombinant IgG3 antibody with Phe-243 replaced by Ala (FA243) was expressed in a CHO-K1 parental cell line. The resulting IgG-Fc-linked carbohydrate was significantly alpha2,3-sialylated (53% of glycans), as indicated by normal- and reverse-phase HPLC analyses. Following transfection of a rat...

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Identifiers

PMID: 11500028
DOI: 10.1006/bbrc.2001.5382

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11500028-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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