Article
Analysis of full-length hepatitis A virus genome in sera from patients with fulminant and self-limited acute type A hepatitis.
Journal of hepatology - 1 Jul 2001
Fujiwara K, Yokosuka O, Fukai K, Imazeki F, Saisho H, Omata M
Abstract excerpt
BACKGROUND/AIMS: Type A hepatitis still poses a considerable problem worldwide. Why some patients progress to fulminant type A hepatitis and others do not is still unknown. To examine whether genomic differences of hepatitis A virus (HAV) are responsible for the severity of the disease, we analyzed the whole HAV genomes from patients with fulminant and self-limited acute type A hepatitis. METHODS: Sera from three...
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