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Article

Analysis of 5' nontranslated region of hepatitis A viral RNA genotype I from South Korea: comparison with disease severities.

PloS one - 28 Dec 2010

Kanda Tatsuo, Jeong Sook-Hyang, Imazeki Fumio, Fujiwara Keiichi, Yokosuka Osamu

Abstract excerpt

The aim of the study was to analyze genotype I hepatitis A virus (HAV) 5' nontranslated region (NTR) sequences from a recent outbreak in South Korea and compare them with reported sequences from Japan. We collected a total of 54 acute hepatitis A patients' sera from HAV genotype I [27 severe disease (prothrombin time INR ≥ 1.50) and 27 mild hepatitis (prothrombin time INR <1.00)], performed nested RT-PCR of 5'...

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PMID: 21203430
DOI: 10.1371/journal.pone.0015139
PMCID: PMC3010980

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