Article
Analysis of hepatitis A virus protein 2B in sera of hepatitis A of various severities.
Journal of gastroenterology - 1 Jul 2007
Fujiwara Keiichi, Yokosuka Osamu, Imazeki Fumio, Miki Makoto, Suzuki Kazuyuki, Okita Kiwamu, Tanaka Eiji, Omata Masao
Abstract excerpt
BACKGROUND: In our recent study of the full-length hepatitis A virus (HAV) genome from some patients with fulminant hepatitis and acute hepatitis, possible associations were suggested between the severity of hepatitis A and the amino acid substitutions in the nonstructural protein 2B. We therefore analyzed HAV 2B from many patients with various clinical disease severities. METHODS: Serum samples from 30 Japanese...
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