Article
Myosin IIB is required for growth cone motility.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Aug 2001
Bridgman P C, Dave S, Asnes C F, Tullio A N, Adelstein R S
Abstract excerpt
Growth cones are required for the forward advancement and navigation of growing axons. Modulation of growth cone shape and reorientation of the neurite are responsible for the change of outgrowth direction that underlies navigation. Change of shape involves the reordering of the cytoskeleton. Reorientation of the neurite requires the generation of tension, which is supplied by the ability of the growth cone to...
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