Article
Cell-Intrinsic Control of Interneuron Migration Drives Cortical Morphogenesis.
Cell - 22 Feb 2018
Silva Carla G, Peyre Elise, Adhikari Mohit H, Tielens Sylvia, Tanco Sebastian, Van Damme Petra, Magno Lorenza, Krusy Nathalie, Agirman Gulistan, Magiera Maria M, Kessaris Nicoletta, Malgrange Brigitte, Andrieux Annie, Janke Carsten, Nguyen Laurent
Abstract excerpt
Interneurons navigate along multiple tangential paths to settle into appropriate cortical layers. They undergo a saltatory migration paced by intermittent nuclear jumps whose regulation relies on interplay between extracellular cues and genetic-encoded information. It remains unclear how cycles of pause and movement are coordinated at the molecular level. Post-translational modification of proteins contributes to...
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