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Article

Candidate genes in polycystic ovary syndrome.

Human reproduction update - 1 Jan 2000

Franks S, Gharani N, McCarthy M

Abstract excerpt

The candidate gene approach has already paid some dividends in trying to understand the complex genetics of polycystic ovary syndrome (PCOS). In terms of steroidogenic abnormalities, CYP11a-encoding P450 side chain cleavage-appears to be a major susceptibility locus. In relation to the well-described metabolic disturbances in PCOS, the insulin gene variable number tandem repeat (VNTR) appears to be a promising...

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Identifiers

PMID: 11476353
DOI: 10.1093/humupd/7.4.405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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