Article
Peripheral blood cell bulk cultures are not suitable for the analysis of the genetic control of T-cell cytokine function.
Immunology letters - 1 Aug 2001
Zipp F, Windemuth C, Dichgans J, Wienker T, Martin R, Müller C
Abstract excerpt
Recently evidence has been provided for a genetic control of T-cell dependent cytokine production by HLA-class II. Candidate genes in multiple sclerosis, a T-cell mediated autoimmune disease, are the disease-associated DR2, DQ6, Dw2 haplotype. Previous observations by us and others imply a HLA-DR...
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