Article
Glycophenotype evaluation in cutaneous tumors using lectins labeled with acridinium ester.
Disease markers - 1 Jan 2013
Lima Luiza Rayanna Amorim, Bezerra Matheus Filgueira, Almeida Sinara Mônica Vitalino, Silva Lúcia Patrícia Bezerra Gomes, Beltrão Eduardo Isidoro Carneiro, Carvalho Júnior Luiz Bezerra
Abstract excerpt
BACKGROUND: Tumor cells show alterations in their glycosylation patterns when compared to normal cells. Lectins can be used to evaluate these glycocode changes. Chemiluminescence assay is an effective technique for quantitative analysis of proteins, nucleic acids, and carbohydrates due to its high sensitivity, specificity, and rapid testing. OBJECTIVE: To use histochemiluminescence based on lectin conjugated to...
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