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Article

Identification and mutagenesis by allelic exchange of choE, encoding a cholesterol oxidase from the intracellular pathogen Rhodococcus equi.

Journal of bacteriology - 1 Aug 2001

Navas J, González-Zorn B, Ladrón N, Garrido P, Vázquez-Boland J A

Abstract excerpt

The virulence mechanisms of the facultative intracellular parasite Rhodococcus equi remain largely unknown. Among the candidate virulence factors of this pathogenic actinomycete is a secreted cholesterol oxidase, a putative membrane-damaging toxin. We identified and characterized the gene encoding this enzyme, the choE monocistron. Its protein product, ChoE, is homologous to other secreted cholesterol oxidases...

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Identifiers

PMID: 11466283
DOI: 10.1128/JB.183.16.4796-4805.2001
PMCID: PMC99534

Genes

CAMP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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