Article
Synthetic peptide strategy for the detection of and discrimination among highly divergent primate lentiviruses.
AIDS research and human retroviruses - 1 Jul 2001
Simon F, Souquière S, Damond F, Kfutwah A, Makuwa M, Leroy E, Rouquet P, Berthier J L, Rigoulet J, Lecu A, Telfer P T, Pandrea I, Plantier J C, Barré-Sinoussi F, Roques P, Müller-Trutwin M C, Apetrei C
Abstract excerpt
We developed a simple, rapid, inexpensive, and highly sensitive and specific strategy for the detection and lineage differentiation of primate lentiviruses (PIV-ELISA). It is based on the use of two indirect ELISA methods using synthetic peptides mapping the gp41/36 region (detection component) and the V3 region (differentiation component) of four lentivirus lineages, namely SIVcpz/HIV-1 (groups M, O, N, and...
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