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Article

Clinical impact of tumour biology in the management of gastroesophageal cancer.

Nature reviews. Clinical oncology - 1 Jun 2016

Lordick Florian, Janjigian Yelena Y

Abstract excerpt

The characterization of oesophageal and gastric cancer into subtypes based on genotype has evolved in the past decade. Insights into the molecular landscapes of gastroesophageal cancer provide a roadmap to assist the development of new drugs and their use in combinations, for patient stratification, and for trials of targeted therapies. Trastuzumab is the only approved treatment for gastroesophageal cancers that...

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Epstein-Barr Virus Infections
Esophageal Neoplasms
Genes, erbB-2
Helicobacter Infections
Immunotherapy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

MAP Kinase Signaling System

Receptor Protein-Tyrosine Kinases

Vascular Endothelial Growth Factor Receptor-2

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Identifiers

PMID: 26925958
DOI: 10.1038/nrclinonc.2016.15
PMCID: PMC5521012

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