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Article

Targeting HER2 expression in cancer: New drugs and new indications.

Bosnian journal of basic medical sciences - 1 Feb 2021

Vranić Semir, Bešlija Semir, Gatalica Zoran

Abstract excerpt

Functional activation of human epidermal growth factor receptor 2 (HER2) has been shown to strongly promote carcinogenesis, leading to the investigation of HER2-directed agents in cancers with HER2 genomic alterations. This has been best documented in the context of HER2 gene amplification in breast and gastric/gastroesophageal junction carcinomas for which several HER2-directed agents are available and have...

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Identifiers

PMID: 32530388
DOI: 10.17305/bjbms.2020.4908
PMCID: PMC7861626

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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