Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel silent substitution (C8516T) in exon 9 of the human PROC gene.

Yonsei medical journal - 1 Jun 2001

Song K S, Kim H K, Song J W, Choi J R, Park Y S

Abstract excerpt

Protein C is a vitamin K dependent serine protease zymogen, which has a regulatory influence over the coagulation cascade via the inhibition of factors Va and VIIIa. Hereditary protein C deficiency is associated with an increased risk of thromboembolic disease. A multitude of families displaying protein C (PROC) gene defects have been reported, and a number of DNA sequence polymorphisms are known to occur in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mutation
Share to Exons
Share to PROC gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein C

Share to Thrombosis

Source

Identifiers

PMID: 11456407
DOI: 10.3349/ymj.2001.42.3.364

Genes

PROC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel silent substitution (C8516T) in exon 9 of the human PROC gene.PMID 11456407Read ↗

Compound heterozygous protein C deficiency with pulmonary embolism caused by a novel PROC gene mutation: Case report and literature review.Semantic proximity Read ↗

Molecular characterization of novel splice site mutation causing protein C deficiency.Semantic proximity Read ↗

A Series of 14 Polish Patients with Thrombotic Events and PC Deficiency-Novel c.401-1G>A PROC Gene Splice Site Mutation in a Patient with AneurysmsSemantic proximity Read ↗

PROC Promoter Single Nucleotide Polymorphisms Associated With Low Protein C Activity But Not Increased Risk of Thromboembolism in Pediatric Population.Semantic proximity Read ↗

Antithrombin deficiency and decreased protein C activity in a young man with venous thromboembolism: a case report.Semantic proximity Read ↗

Genetic background analysis of protein C deficiency demonstrates a recurrent mutation associated with venous thrombosis in Chinese population.Semantic proximity Read ↗

A novel mutation in protein C gene (PROC) causing severe phenotype in neonatal period.Semantic proximity Read ↗

Recurrent PROC and novel PROS1 mutations in Vietnamese patients diagnosed with idiopathic deep venous thrombosis.Semantic proximity Read ↗

A novel homozygous missense mutation in the protein C (PROC) gene causing recurrent venous thrombosis.Semantic proximity Read ↗

Novel insights into inherited protein C deficiency from an interactive PROC variant database.Semantic proximity Read ↗

Distinct frequencies and mutation spectrums of genetic thrombophilia in Korea in comparison with other Asian countries both in patients with thromboembolism and in the general population.Semantic proximity Read ↗

Clinical and genetic features of protein C deficiency in 23 unrelated Chinese patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.