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Article

Antithrombin deficiency and decreased protein C activity in a young man with venous thromboembolism: a case report.

Frontiers of medicine - 1 Jun 2018

Wang Dong, Tian Min, Cui Guanglin, Wang Dao Wen

Abstract excerpt

Antithrombin and protein C are two crucial members in the anticoagulant system and play important roles in hemostasis. Mutations in SERPINC1 and PROC lead to deficiency or dysfunction of the two proteins, which could result in venous thromboembolism (VTE). Here, we report a Chinese 22-year-old young man who developed recurrent and serious VTE in cerebral veins, visceral veins, and deep veins of the lower...

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Source

Identifiers

PMID: 28861852
DOI: 10.1007/s11684-017-0553-4

Genes

PROC
SERPINC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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