Article
Inverse expression of P(k) and Luke blood group antigens on human RBCs.
Transfusion - 1 Jul 2001
Cooling L L, Kelly K
Abstract excerpt
BACKGROUND: Luke (LKE) is a high-frequency RBC antigen, related to the P blood group system. A LKE-negative phenotype is found in 1 to 2 percent of donors and may be associated with increased P(k). Because P(k) and similar glycolipids are receptors for shiga toxin on cell membranes, a LKE-negative phenotype could have implications for infections by Shigella dysenteriae and enterohemorrhagic Escherichia coli....
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