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Article

Identification of a defect in the intracellular trafficking of a Kell blood group variant.

Blood - 1 Jul 1999

Yazdanbakhsh K, Lee S, Yu Q, Reid M E

Abstract excerpt

Blood group polymorphisms have been used as tools to study the architecture of the red blood cell (RBC) membrane. Some blood group variants have reduced antigen expression at the cell surface. Understanding the underlying mechanism for this reduced expression can potentially provide structural information and help to elucidate protein trafficking pathways of membrane proteins. The Kp(a+) phenotype is a variant in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10381527

Genes

KEL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of a defect in the intracellular trafficking of a Kell blood group variant.PMID 10381527Read ↗

Expansion of the Kell blood group system: two new high-prevalence antigens and two novel K0 (Kellnull ) phenotypes.Semantic proximity Read ↗

A structure-based in silico analysis of the Kell blood group system.Semantic proximity Read ↗

Molecular basis of two novel and related high-prevalence antigens in the Kell blood group system, KUCI and KANT, and their serologic and spatial association with K11 and KETI.Semantic proximity Read ↗

Insights into the structure and function of membrane polypeptides carrying blood group antigens.Semantic proximity Read ↗

Molecular basis of the Kell-null phenotype: a mutation at the splice site of human KEL gene abolishes the expression of Kell blood group antigens.Semantic proximity Read ↗

A combination of the effects of rare genotypes at the XK and KEL blood group loci results in absence of Kell system antigens from the red blood cells.Semantic proximity Read ↗

The Kell blood group system: Kell and XK membrane proteins.Semantic proximity Read ↗

Molecular basis of Kell blood group phenotypes.Semantic proximity Read ↗

Novel KEL allele associated with loss of Kpb identified in a white blood donor.Semantic proximity Read ↗

Genetic Variants Within the Erythroid Transcription Factor, KLF1, and Reduction of the Expression of Lutheran and Other Blood Group Antigens: Review of the In(Lu) PhenotypeSemantic proximity Read ↗

Point mutations in KEL exon 8 determine a high-incidence (RAZ) and a low-incidence (KEL25, VLAN) antigen of the Kell blood group system.Semantic proximity Read ↗

Molecular basis of the Kell (K1) phenotype.Semantic proximity Read ↗

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