Decline in number of Na-K pumps on low-K+ sheep reticulocytes during maturation is modulated by Lp antigen.

Abstract excerpt

The number of the Na-K pumps on sheep red blood cells declines markedly during cell maturation. In addition, in red blood cells of the low-K+ (LK) phenotype, there is an increase during maturation in the affinity of the pumps for intracellular K+. This increase does not occur in cells of the high-K+ (HK) phenotype. This HK/LK polymorphism is associated with the M/L blood group antigen system. The Lp antigen,...

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