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Article

Neurotrophism without neurotropism: BDNF promotes survival but not growth of lesioned corticospinal neurons.

The Journal of comparative neurology - 6 Aug 2001

Lu P, Blesch A, Tuszynski M H

Abstract excerpt

Neurotrophic factors exert many effects on the intact and lesioned adult central nervous system (CNS). Among these effects are prevention of neuronal death (neurotrophism) and promotion of axonal growth (neurotropism) after injury. To date, however, it has not been established whether survival and axonal growth functions of neurotrophins can be independently modulated in injured adult neurons in vivo. To address...

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Source

Identifiers

PMID: 11447589
DOI: 10.1002/cne.1080

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Neurotrophism without neurotropism: BDNF promotes survival but not growth of lesioned corticospinal neurons.PMID 11447589Read ↗

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