Article
Clinical variables, not RAAS polymorphisms, predict blood pressure response to ACE inhibitors in Sardinians.
Pharmacogenomics - 1 Oct 2008
Filigheddu Fabiana, Argiolas Giuseppe, Bulla Emanuela, Troffa Chiara, Bulla Patrizia, Fadda Simone, Zaninello Roberta, Degortes Simona, Frau Francesca, Pitzoi Silvia, Glorioso Nicola
Abstract excerpt
AIM: No definite factors predict blood pressure response to angiotensin-converting enzyme-inhibitors. The aim of this study was to test the association of gene polymorphisms of the renin-angiotensin-aldosterone system with essential hypertension and anthropometric variables, intermediate phenotypes and gene polymorphisms with blood pressure after fosinopril in a genetically homogeneous cohort. METHODS: A total of...
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