Article
Contribution of Mn-Cofactored Superoxide Dismutase (SodA) to the Virulence of <i>Streptococcus agalactiae</i>
1 Aug 2001
Abstract excerpt
Superoxide dismutases convert superoxide anions to molecular oxygen and hydrogen peroxide, which, in turn, is metabolized by catalases and/or peroxidases. These enzymes constitute one of the major defense mechanisms of cells against oxidative stress and hence play a role in the pathogenesis of certain bacteria. We previously demonstrated that group B streptococci (GBS) possess a single Mn-cofactored superoxide...