Article
Self-association of CIITA and its transactivation potential.
Molecular and cellular biology - 1 Aug 2001
Sisk T J, Roys S, Chang C H
Abstract excerpt
The major histocompatibility complex (MHC) class II transactivator (CIITA) regulates the expression of genes involved in the immune response, including MHC class II genes and the interleukin-4 gene. Interactions between CIITA and sequence-specific, DNA-binding proteins are required for CIITA to function as an activator of MHC class II genes. CIITA also interacts with the coactivators CBP (also called p300), and...
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