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Article

Polymorphisms in the prothrombin gene and their association with plasma prothrombin levels.

Thrombosis and haemostasis - 1 Jun 2001

Ceelie H, Bertina R M, van Hylckama Vlieg A, Rosendaal F R, Vos H L

Abstract excerpt

To find genetic causes of high plasma prothrombin levels, an established prothrombotic risk factor. we searched for sequence variations in the prothrombin gene. We selected subjects with the 20210-GG genotype (since the 20210-A allele is already known to be associated with high levels) and elevated prothrombin levels (> or = 130 U/dl) from the Leiden Thrombophilia Study (LETS). No mutations were found in the 1 kb...

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PMID: 11434686

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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