Article
Selecting for functional alternative splices in ESTs.
Genome research - 1 Dec 2002
Kan Zhengyan, States David, Gish Warren
Abstract excerpt
The expressed sequence tag (EST) collection in dbEST provides an extensive resource for detecting alternative splicing on a genomic scale. Using genomically aligned ESTs, a computational tool (TAP) was used to identify alternative splice patterns for 6400 known human genes from the RefSeq database. With sufficient EST coverage, one or more alternatively spliced forms could be detected for nearly all genes...
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