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Plasma Cell-Free DNA Levels Are Elevated in Acute Puumala Hantavirus Infection

7 Feb 2012

Abstract excerpt

INTRODUCTION: Puumala hantavirus (PUUV) causes a hemorrhagic fever with renal syndrome called nephropathia epidemica (NE). The aim of the present study was to evaluate plasma cell-free DNA (cf-DNA) levels and urinary cf-DNA excretion in acute NE as well as their associations with the severity of the disease. METHODS: Total plasma cf-DNA was quantified directly in plasma of 61 patients and urine of 20 patients...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 22347483
DOI: 10.1371/journal.pone.0031455

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