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Article

Fluorogenic PCR-Based Quantitative Detection of a Murine Pathogen, <i>Helicobacter hepaticus</i>

1 Jul 2001

Abstract excerpt

Helicobacter hepaticus infection in mice is being used as an animal model for elucidating the pathogenesis of gastrointestinal and biliary diseases in humans. H. hepaticus, which forms a spreading film on selective agar, is not amenable to routine quantitative counts of organisms in tissues using a CFU method. In this study, a fluorogenic PCR-based assay was developed to quantitatively detect H. hepaticus in...

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PMID: 11427576
DOI: 10.1128/jcm.39.7.2598-2602.2001

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