Article
Identification of genes induced in peripheral nerve after injury. Expression profiling and novel gene discovery.
The Journal of biological chemistry - 7 Sept 2001
Araki T, Nagarajan R, Milbrandt J
Abstract excerpt
Peripheral nerve injury results in axonal degeneration and in phenotypic changes of the surrounding Schwann cells, whose presence is critical for nerve regeneration. To identify genes induced after nerve injury in Schwann cells, we developed a strategy that included differential screening of a subtractive library enriched for cDNAs expressed in injured nerve, sequence analysis, and expression profiling. By using...
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