Article
Primary Tau Pathology, Not Copathology, Correlates With Clinical Symptoms in PSP and CBD.
Journal of neuropathology and experimental neurology - 1 Mar 2020
Robinson John L, Yan Ning, Caswell Carrie, Xie Sharon X, Suh EunRan, Van Deerlin Vivianna M, Gibbons Garrett, Irwin David J, Grossman Murray, Lee Edward B, Lee Virginia M-Y, Miller Bruce, Trojanowski John Q
Abstract excerpt
Distinct neuronal and glial tau pathologies define corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP). Additional Alzheimer disease, TDP-43, and Lewy body copathologies are also common. The interplay of these pathologies with clinical symptoms remains unclear as individuals can present with corticobasal syndrome, frontotemporal dementia, PSP, or atypical Parkinsonism and may have additional...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.