Article
Haemoglobin Q-Thailand and hereditary spherocytosis in a Chinese family.
Clinical and laboratory haematology - 1 Feb 2001
Leung K F, Au W Y, Chan A Y, Chan L C, Waye J S, Chui D H, Ma S K
Abstract excerpt
A Chinese family with concurrent hereditary spherocytosis (HS) and haemoglobin (Hb) Q-Thailand is described. The Hb Q-Thailand mutation was found on the remaining alpha1 globin gene on a chromosome 16 containing the (-alpha 4.2) deletion. Active haemolysis in members of this family is segregated with the HS phenotype, and the Hb Q-Thailand in the heterozygous state does not seem to show any modulating effect on HS.
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