Article
Mouse singletons and twins developed from isolated diploid blastomeres supported with tetraploid blastomeres.
The International journal of developmental biology - 1 Jan 2001
Tarkowski A K, Ozdzenski W, Czołowska R
Abstract excerpt
The aim of this study was to obtain mice, hopefully identical multiplets, from single diploid blastomeres isolated at the 4-cell stage, or from pairs of sister blastomeres isolated at the 8-cell stage. To this end isolated blastomeres were aggregated with one or two tetraploid carrier embryos produced by electrofusion of 2-cell embryos. Diploid embryos were albino and homozygous for the "a" allele of...
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