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Article

Protection from superoxide damage associated with an increased level of the YggX protein in Salmonella enterica.

Proceedings of the National Academy of Sciences of the United States of America - 3 Jul 2001

Gralnick J, Downs D

Abstract excerpt

The deleterious effect of superoxide radicals on cell growth and survival is predominantly caused by rapid oxidation of labile [Fe-S] clusters in proteins. Oxidation of these clusters releases Fe(II) ions, which participate in Fenton chemistry that damages DNA. Here it is shown that elevated levels of the YggX protein increase the resistance of Salmonella enterica to superoxide stress, reverse enzymatic defects...

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Identifiers

PMID: 11416172
DOI: 10.1073/pnas.151243198
PMCID: PMC35462

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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