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Article

Products of US22 genes M140 and M141 confer efficient replication of murine cytomegalovirus in macrophages and spleen.

Journal of virology - 1 Jul 2001

Hanson L K, Slater J S, Karabekian Z, Ciocco-Schmitt G, Campbell A E

Abstract excerpt

Efficient replication of murine cytomegalovirus (MCMV) in macrophages is a prerequisite for optimal growth and spread of the virus in its natural host. Simultaneous deletion of US22 gene family members M139, M140, and M141 results in impaired replication of MCMV in macrophages and mice. In this study, we characterized the proteins derived from these three genes and examined the impact of individual gene deletions...

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Identifiers

PMID: 11413295
DOI: 10.1128/JVI.75.14.6292-6302.2001
PMCID: PMC114351

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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