Article
Total tetra knockout of GP138 multigene family implicated in cell interactions in Dictyostelium discoideum.
Gene - 13 Jun 2001
Hata T, Takahashi M, Tanaka Y, Urushihara H
Abstract excerpt
The cellular slime mold Dictyostelium discoideum reproduces sexually under submerged and dark conditions. A cell surface glycoprotein gp138 has been identified as a target molecule for cell fusion-blocking antibodies, and is considered to be indispensable for the sexual cell fusion in this organism. Currently, four isoforms of gp138, DdFRP1alpha, DdFRP1beta, DdFRP2, and DdFRP3, are known. Genes encoding the...
Topics
- Amino Acid Sequence
- Animals
- Cell Adhesion Molecules
- Chromosome Deletion
- Chromosome Mapping
- DNA
- Dictyostelium
- Gene Expression
- Gene Order
- Molecular Sequence Data
- Multigene Family
- Mutation
- RNA
- Sequence Alignment
- Sequence Analysis, DNA
- Sequence Analysis, Protein
- Sequence Homology, Amino Acid