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Article

Hyperactive recombination in the mitochondrial DNA of the natural death nuclear mutant of Neurospora crassa.

Molecular and cellular biology - 1 Nov 1993

Bertrand H, Wu Q, Seidel-Rogol B L

Abstract excerpt

In Neurospora crassa, a recessive mutant allele of a nuclear gene, nd (natural death), causes rapid degeneration of the mitochondrial DNA, a process that is manifested phenotypically as an accelerated form of senescence in growing and stationary mycelia. To examine the mechanisms that are involved in the degradation of the mitochondrial chromosome, several mitochondrial DNA restriction fragments unique to the...

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Identifiers

PMID: 8413272
DOI: 10.1128/mcb.13.11.6778-6788.1993
PMCID: PMC364740

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