Article
Angiotensin converting enzyme insertion/deletion polymorphism is associated with plasma antigen levels of plasminogen activator inhibitor-1 in healthy Japanese population.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Mar 2000
Matsubara Y, Hayakawa T, Tsuda T, Takeshita E, Watanabe G, Murata M, Watanabe K, Ikeda Y
Abstract excerpt
Plasminogen activator inhibitor-1 (PAI-1) has a central role in the regulation of the fibrinolytic enzyme system. An elevated plasma PAI-1 level is associated with thrombotic disorders. In vitro and in vivo studies indicate that the renin-angiotensin system is involved in the regulation of PAI-1....
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