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Article

Differential Effects of Primary Human Immunodeficiency Virus Type 1 nef Sequences on Downregulation of CD4 and MHC Class I

1 Jun 2001

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 11396948
DOI: 10.1006/bbrc.2001.5026

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Related research

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Differential Effects of Primary Human Immunodeficiency Virus Type 1 nef Sequences on Downregulation of CD4 and MHC Class IPMID 11396948Read ↗

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One Protein to Rule them All: Modulation of Cell Surface Receptors and Molecules by HIV NefSemantic proximity Read ↗

Human leukocyte antigen (HLA) class I down-regulation by human immunodeficiency virus type 1 negative factor (HIV-1 Nef): what might we learn from natural sequence variants?Semantic proximity Read ↗

HIV-1 Nef disrupts intracellular trafficking of major histocompatibility complex class I, CD4, CD8, and CD28 by distinct pathways that share common elements.Semantic proximity Read ↗

CD4 Down-Modulation by Human Immunodeficiency Virus Type 1 Nef Correlates with the Efficiency of Viral Replication and with CD4 + T-Cell Depletion in Human Lymphoid Tissue Ex VivoSemantic proximity Read ↗

Mechanisms of Immune Evasion in HIV-1: The Role of Virus-Host Protein InteractionsSemantic proximity Read ↗

Downregulation of cell surface CD4 by nefSemantic proximity Read ↗

Human immunodeficiency virus Nef induces rapid internalization of the T-cell coreceptor CD8alphabeta.Semantic proximity Read ↗

Simian and human immunodeficiency virus Nef proteins use different surfaces to downregulate class I major histocompatibility complex antigen expression.Semantic proximity Read ↗

Structural similarity of two T cell signaling regulators suggests a conserved and interactive mechanism of immunosuppression.Semantic proximity Read ↗

Expression of Nef downregulates CXCR4, the major coreceptor of human immunodeficiency virus, from the surfaces of target cells and thereby enhances resistance to superinfection.Semantic proximity Read ↗

Human immunodeficiency virus type 1 Nef-mediated downregulation of CD4 correlates with Nef enhancement of viral pathogenesis.Semantic proximity Read ↗

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