Article
Increased D allele frequency of the angiotensin-converting enzyme gene in pulmonary fibrosis.
Human pathology - 1 May 2001
Morrison C D, Papp A C, Hejmanowski A Q, Addis V M, Prior T W
Abstract excerpt
An insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme has previously been studied extensively in relationship to cardiovascular and renal disease. The deletion/deletion (D/D) genotype is associated with a poor outcome in immunoglobulin (Ig) A nephropathy. However, the association of this genetic marker in cardiovascular and renal disease has generated controversy, with the exception of the...
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