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Article

Angiotensin-converting enzyme DD genotype in patients with primary pulmonary hypertension: increased frequency and association with preserved haemodynamics.

Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Mar 2003

Abraham William T, Raynolds Mary V, Badesch David B, Wynne Kristine M, Groves Bertron M, Roden Robert L, Robertson Alastair D, Lowes Brian D, Zisman Lawrence S, Voelkel Norbert F, Bristow Michael R, Perryman M Benjamin

Abstract excerpt

UNLABELLED: HYPOTHESIS/INTRODUCTION: A polymorphic marker within the angiotensin- converting enzyme (ACE) gene has been associated with circulating and tissue ACE activity and with a variety of forms of cardiovascular disease. Since angiotensin II (Ang II) causes pulmonary vasoconstriction and vascular and myocardial remodelling, we postulated a role for the renin-angiotensin system and the ACE DD genotype in the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12692750
DOI: 10.3317/jraas.2003.003

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Angiotensin-converting enzyme DD genotype in patients with primary pulmonary hypertension: increased frequency and association with preserved haemodynamics.PMID 12692750Read ↗

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