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Article

Mutation analysis of <i>C‐KIT</i> in patients with myelodysplastic syndromes without mastocytosis and cases of systemic mastocytosis

1 May 2001

Abstract excerpt

The proto-oncogene C-KIT encodes a tyrosine kinase receptor that is expressed on mast cells and haematopoietic stem cells and can show somatic mutations in patients with mastocytosis. Only scattered information is available about mutations in C-KIT in patients with other myeloid neoplasms. Moreover, the prevalence of mutations in C-KIT in bone marrow specimens of individuals with systemic mastocytosis is largely...

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Identifiers

PMID: 11380399
DOI: 10.1046/j.1365-2141.2001.02783.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Mutation analysis of <i>C‐KIT</i> in patients with myelodysplastic syndromes without mastocytosis and cases of systemic mastocytosisPMID 11380399Read ↗

Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder.Semantic proximity Read ↗

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