Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene transfer and expression of platelet-derived growth factors modulate periodontal cellular activity.

Journal of dental research - 1 Mar 2001

Zhu Z, Lee C S, Tejeda K M, Giannobile W V

Abstract excerpt

Platelet-derived growth factor (PDGF) is a potent stimulator of wound healing. PDGF gene therapy may promote greater periodontal regeneration than local protein application, due to sustained growth factor delivery to the target tissue. This investigation tested the ability of recombinant adenoviruses (rAds) encoding PDGF-A or PDGF-1308 (a PDGF-A dominant-negative mutant that disrupts endogenous PDGF bioactivity)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenoviridae
Share to Osteoblasts
Share to Periodontal Ligament

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Platelet-Derived Growth Factor

Share to Regeneration

Share to Statistics as Topic

Share to Transduction, Genetic

Share to Wound Healing

Source

Open in PubMed Open full text

Identifiers

PMID: 11379891
DOI: 10.1177/00220345010800030901
PMCID: PMC2584017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene transfer and expression of platelet-derived growth factors modulate periodontal cellular activity.PMID 11379891Read ↗

Platelet-derived growth factor-B gene delivery sustains gingival fibroblast signal transduction.Semantic proximity Read ↗

Engineering of tooth-supporting structures by delivery of PDGF gene therapy vectors.Semantic proximity Read ↗

Platelet-Derived Growth Factor Gene Delivery Stimulates <i>ex Vivo</i> Gingival RepairSemantic proximity Read ↗

Lentiviral Transfection with the PDGF-B Gene Improves Diabetic Wound HealingSemantic proximity Read ↗

PDGF-BB and IL-4 co-overexpression is a potential strategy to enhance mesenchymal stem cell-based bone regenerationSemantic proximity Read ↗

The potential contributions of cell and molecular biology to periodontal tissue regeneration.Semantic proximity Read ↗

Growth Factors And Wound Healing: Platelet-Derived Growth Factor As A Model CytokineSemantic proximity Read ↗

Growth Factors and Wound Healing: Platelet-Derived Growth Factor as a Model CytokineSemantic proximity Read ↗

Adenovirus-mediated transfer of hepatocyte growth factor gene to human dental pulp stem cells under good manufacturing practice improves their potential for periodontal regeneration in swineSemantic proximity Read ↗

Mitogenic and Chemotactic Responses of Human Periodontal Ligament Cells to the Different Isoforms of Platelet-derived Growth FactorSemantic proximity Read ↗

Particle-mediated gene transfer of PDGF isoforms promotes wound repair.Semantic proximity Read ↗

Biological mediators for periodontal regenerationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.